What is metastasis in relation to cancer?

Metastasis refers specifically to the process by which cancer cells spread from the original (primary) site of the tumor to other parts of the body, establishing new tumors in those distant locations. This migration is a critical aspect of cancer progression and is a key factor that complicates treatment efforts, as it can lead to multiple affected areas requiring different management strategies.

Understanding metastasis is essential in cancer biology and treatment, as it highlights the aggressive nature of certain cancers and the importance of early detection and intervention. The ability of cancer cells to invade surrounding tissues and travel through the lymphatic and blood systems is what distinguishes malignant tumors from benign ones, which do not possess this ability.